In Brawl For Seau Brain, A Proxy War Over Concussion Science

By Steve Fainaru and Mark Fainaru-Wada


ESPN reporters Mark Fainaru-Wada and Steve Fainaru are writing a book about football and brain injuries, to be published in 2013 by Crown Books, a division of Random House. FRONTLINE, in partnership with ESPNā€™s Outside the Lines, is producing a documentary based on the reportersā€™ research. This article is a product of these partnerships.





Inside the autopsy room of the San Diego County medical examinerā€™s office, Bennet Omalu, a forensic pathologist, carefully sliced Junior Seauā€™s brain with a long knife. It was late morning on May 3, 2012; Seauā€™s autopsy, which began just after 9, was nearly over. Omalu wore dark blue scrubs, rubber gloves and a clear plastic face mask as he went about his work in the cool, windowless room, picking up half of Seauā€™s brain and placing it in a small tub filled with formaldehyde and water.

Omalu, 44, was the first researcher to identify brain damage in a former NFL player. When he published his results, in July 2005, the NFL attacked him and insisted he was wrong. His research has since been vindicated many times over, with each new discovery of the crippling neurodegenerative disease in a dead football player. Omalu arrived at Seauā€™s autopsy with a special ā€œbrain briefcaseā€ he carries on such occasions. His intention was to fly Seauā€™s brain back to San Francisco that night and share it with a Nobel Prize-winning researcher who also coveted the valuable specimen.

Just then, the medical examinerā€™s chaplain, Joe Davis, walked into the room.

ā€œHouston, we have a problem,ā€ Davis said.

Seauā€™s son Tyler had just called, Davis told Omalu and Craig Nelson, the deputy medical examiner.

ā€œI talked to the NFL,ā€ Tyler Seau, then 22, told the chaplain. The league, he said, informed him that Omaluā€™s ā€œresearch is bad and his ethics are bad.ā€ Tyler was in a rage. Omalu ā€œis not to be in the same fā€”ing room as my dad!ā€ he screamed. ā€œHeā€™s not to fā€”ing touch my dad! Heā€™s not to have anything to do with my dad!ā€

Omalu left and returned home, his brain briefcase empty.

From that point on, the NFL played a powerful role in determining what happened to Junior Seauā€™s brain ā€” who studied it and where. In the hours, days and weeks after Seau shot himself in the chest with a .357 Magnum revolver ā€” the shocking end to the life of one of the most admired players in history ā€” the league muscled aside independent researchers, ignored a previous commitment to Boston University and directed Seauā€™s brain to the National Institutes of Health ā€” four months before the NFL donated $30 million to that institution for concussion and other research.

The NFLā€™s intervention in the fate of Seauā€™s brain ā€” the most prized specimen yet in the race to document the relationship between football and brain damage ā€” was part of an aggressive strategy to dictate who leads the science of concussions. By shunting aside Omalu, whose discovery sparked the concussion crisis; Boston University researchers, the leading experts on football and brain damage; a Nobel laureate; and other suitors, the league directed Seauā€™s brain away from scientists who have driven the national debate about the risks of playing football ā€” the central issue to the NFLā€™s future.

ā€œOutside the Linesā€ and ā€œFrontlineā€ pieced together the odyssey of Seauā€™s brain from interviews, documents and private emails.

What emerges is essentially a scientific backroom brawl in which the NFL prevailed over a half-dozen researchers vying for Seauā€™s brain. To the league and the Seau family ā€” and even some of the losers ā€” this was the best possible outcome. The NFL ended an ugly free-for-all that brought added pain to Seauā€™s relatives, who received unsolicited calls from brain researchers, including Omalu, within hours of his death. With researchers unwilling to share tissue and bad-mouthing one another to Seauā€™s family, the intervention by league representatives led to a blind study by one of the most respected research institutions in the country. Five specialists consulted by the NIH found what Omalu himself suspected: Seau suffered from chronic traumatic encephalopathy, or CTE, the disease found in dozens of former players.

ā€œObviously, the NFL wants to be real careful as to not look as though they were inserting themselves in the middle of this, where theyā€™re trying to cover something up,ā€ said Kevin Guskiewicz, one of three members of the NFLā€™s Head, Neck and Spine Committee who helped steer Seauā€™s brain to the NIH. ā€œI can assure you that is not the case right now.ā€

But thereā€™s a dĆ©jĆ  vu quality to the NFLā€™s recent strategy. A federal lawsuit filed against the league by more than 4,000 retired players and their families (including Seauā€™s) revolves around the NFLā€™s previous scientific exploration. The players charge that the leagueā€™s original concussion committee, which was disbanded in 2009, conducted fraudulent research to hide the connection between football and brain damage. That 15 years of research has been largely discarded, even by the league. When Mitchel Berger, chairman of the department of neurological surgery at the University of California San Francisco, joined the NFLā€™s new concussion committee in 2010, he and his colleagues ā€œessentially started from zero,ā€ Berger said.

Faced with the threat of the lawsuit and mounting concerns about the long-term health effects of the sport, the NFL is again using its vast resources to insert itself in the science of head trauma.

ā€œI guess the National Institute of Health is now involved; I guess they somehow got drafted by the NFL,ā€ said Bob Fitzsimmons, a Wheeling, W.Va., lawyer who represented Mike Webster, the first NFL player diagnosed with CTE, and co-founded the nonprofit Brain Injury Research Institute with Omalu and Dr. Julian Bailes, a prominent neurosurgeon. ā€œThey had an early draft, I think, and they drafted the NIH and paid them pretty good salary, too, from what I hear.ā€

The NFL also recently announced a $60 million research partnership with General Electric and Under Armour, and is working with the U.S. Army on concussion initiatives.

An NFL spokesman, Greg Aiello, said members of the Head, Neck and Spine Committee work independently and the league played no role in directing Seauā€™s brain to the NIH. Guskiewicz said he acted on his own as a research scientist and not under the direction of the league. The NFL Head, Neck and Spine Committee is funded by the NFL, reports to the commissioner and filters communication through the NFLā€™s media office, which sometimes monitors interviews and correspondence with committee members. None of the committee members is paid by the league, but they submit expenses through the league office.

According to Dr. Rich Ellenbogen, the committeeā€™s co-chairman, NFL Commissioner Roger Goodell sought guidance from the committee as far back as 2010 about where to direct the leagueā€™s resources. The NIH was recommended. At the same time, Ellenbogen and other committee members discussed employing the NIH as a scientific clearinghouse for research into football and brain damage.

Seauā€™s death became a catalyst for turning the NFLā€™s vision into reality.

In the final months of his life, Seau had become unrecognizable to those closest to him. He rarely saw his four children and frequently disappeared on partying and gambling binges, spending tens of thousands of dollars at a time. His erratic moods, inattentiveness and inexplicable bursts of anger had caused his most trusted confidante, Bette Hoffman, the head of his charitable foundation whom Seau called ā€œMom,ā€ to quit and change her phone number to avoid his calls. In San Diego, Seau was still beloved as a great athlete and local ambassador who raised millions of dollars for disadvantaged kids through the Junior Seau Foundation. His smile and charisma, which lit up the entire city, seemed undiminished. But to those who loved him, he was obviously in trouble; many now believe his car crash off a cliff in 2010 was a suicide attempt.

As word spread on May 2 that Seauā€™s girlfriend had found him shot in the chest on a queen-sized bed at his beachfront home in Oceanside, Calif., Seauā€™s extended Samoan family, friends, neighbors and San Diego Chargers fans descended on the house.

Nelson, the deputy medical examiner, arrived at 11:46 a.m. A medical examiner investigatorā€™s report described the scene: ā€œThere was bedding lying on the floor on the left side of the bed as I faced it. On top of the bed were pillows stained with blood. The fitted sheet on the bed was blood stained. A gray stocking cap and a Smith & Wesson Model 19-5 .357 magnum revolver ā€¦ lay on its left side with five live rounds in the cylinder and one spent round near the right-sided head of the bed as I faced it, and next to a pillow.ā€

Seau was placed on a gurney in a body bag and brought down to the garage. Only his head was exposed. The house was warm and filled with police, medical personnel and family, and decorated with Seauā€™s trophies and memorabilia: his Chargers MVP trophy, game photos, a New England Patriots helmet signed by the team. The crowd outside had swelled to some 400 people. Seauā€™s family opened the garage for a spontaneous public viewing. One by one, for nearly an hour, the tearful crowd filed past; some bent over to kiss Seauā€™s forehead or cheek. ā€œIt was a pretty intense moment,ā€ one witness said. ā€œI looked down and I was like, ā€˜Man, thatā€™s Junior Seau.ā€™ Thereā€™s nobody that looks like him. It really affected me, the enormity of it.ā€

As Tyler Seau looked down, he felt pain and regret. Like the rest of his siblings, he had been fighting for his fatherā€™s attention, dealing with the absences and volcanic bursts of anger.

ā€œI guess the hardest thing was just there was just no closure,ā€ he said, crying softly during an interview.

When the viewing ended, Seauā€™s body was taken away. Tyler was still at the house when his cellphone rang. At first it was difficult to hear; reception at the beach house was spotty. But soon he could make out the thickly accented voice.

It was Bennet Omalu, introducing himself and expressing his condolences.

He had a request.

Omalu was a 36-year-old junior pathologist at the Allegheny County Coronerā€™s Office in Pittsburgh when he identified Webster, the Hall of Fame Steelers center, with CTE. That discovery forever changed how people look at football and continues to haunt the NFL.

Omalu is now chief medical examiner in San Joaquin County, Calif. But in many ways, he is still a foreigner, especially in the closed world of concussion research, which is dominated by older, white men. A devout Catholic and native of Nigeriaā€™s Igbo tribe, he blends science and mysticism and is prone to hyperbole and indiscretion. Omalu believes he can communicate with the spirits of the people he autopsies. In 2009, he displayed photos of Webster lying on the autopsy table during a meeting of the NFL Players Association in Palm Beach, Fla., stunning many of the players, scientists and widows in attendance.

No one has been able to discredit Omaluā€™s research, however. When Bailes, the neurosurgeon who helped found the Brain Injury Research Institute with Omalu and Fitzsimmons, heard that Seau had killed himself, he phoned Omalu immediately.

ā€œWe need to secure this brain,ā€ said Bailes, the co-director of NorthShore Neurological Institute in Evanston, Ill.

To many, Seauā€™s brain was the premier specimen in concussion research. At stake were research dollars and the prestige of diagnosing Seau, who was 43 at the time of his death and the most significant player thrust into the NFLā€™s concussion crisis. Seau was a certain Hall of Famer who spent 20 years in the NFL. He combined strength and speed to become one of the gameā€™s most physical players. The fact that he never had a diagnosed concussion raised more questions for the NFL and scientists seeking to study his brain.

Omalu and Bailes called Tyler Seau together. ā€œWe introduced ourselves, explained what we were doing, about CTE, that we would like him to grant us consent to examine his fatherā€™s brain,ā€ Omalu said. He described Tyler as ā€œvery politeā€ and receptive during the call.

But Tyler said he felt pressured by Omalu. ā€œHe was very pushy and he really wanted me to make a decision that night. He pretty much said that we have to do it now because if itā€™s not done the right way we could lose a lot of the tissue and things like that.ā€

Omalu faxed Tyler a consent form to harvest his fatherā€™s brain. Emails obtained by ā€œOutside the Linesā€ and ā€œFrontlineā€ show that Tyler initially was prepared to sign. At 8:38 that night, he informed Omalu: ā€œmy guy is on his way here right now so I can sign it and fax it back to you.ā€ An hour later, Tyler wrote that Omalu needed to talk to David Chao, the San Diego Chargers doctor, to ā€œcross our Ts and dot our Is before proceeding.ā€

Tyler said he called Chao for advice because ā€œhe was my dadā€™s team doctor 13 years. They were pretty close.ā€ Chao has come under criticism in and out of the medical community for issues unrelated to Seauā€™s care. DeMaurice Smith, the executive director of the NFL Players Association, called for Chao to be replaced as team doctor over allegations of malpractice and negligence. Earlier this year, a panel of independent doctors established under the collective bargaining agreement exonerated Chao.

The night of Seauā€™s death, Omalu spoke with Chao. ā€œThat was one of the most arrogant phone calls Iā€™ve ever been involved with in my life,ā€ Omalu said. ā€œThis guy was yelling, was extremely arrogant, pretty much questioning who I was.ā€

Chao declined to comment for this story.

After emailing samples of his research to Chao, Omalu still believed he had ā€œverbal consentā€ from Tyler to take Seauā€™s brain. He packed for the flight from San Francisco to San Diego the following morning to do just that.

By the time Nelson, the deputy medical examiner, returned from Seauā€™s home, a half-dozen phone messages were waiting for him from researchers hoping to study the brain.

One of the researchers in pursuit, emails show, was Stanley Prusiner, winner of the 1997 Nobel Prize in Physiology or Medicine. Prusiner, a 70-year-old neurologist who is director of the Institute for Neurodegenerative Diseases at the University of California San Francisco, won the award for his discovery of prions ā€” a class of proteins that cause brain disease.

Prusiner joined Omalu in what became a tag-team approach to securing Seauā€™s brain. Shortly after Seauā€™s death, Prusiner, according to emails and interviews, placed calls to Davis, the chaplain at the medical examinerā€™s office, to try to arrange a meeting with the Seau family. Prusinerā€™s assistant also called and emailed Tyler Seau.

ā€œPlease it is vital you get to the Seau family,ā€ Omalu wrote Prusiner. ā€œI think they will give you/us the brain if you directly speak to them and play the nobel price (sic) card ā€

Prusiner responded by email 12 minutes later that he planned to fly to San Diego to try to meet with the Seau family.

But others, too, had begun to make bids for the specimen. The day after Seauā€™s death, Boston Universityā€™s Center for the Study of Traumatic Encephalopathy reached out to representatives of the family. Chris Nowinski, a 34-year-old former professional wrestler and concussion activist, had once worked with Omalu. When the two split acrimoniously, Nowinski merged his own group, the Sports Legacy Institute, with BU. Working with another pathologist, Dr. Ann McKee, the Boston group had diagnosed more CTE cases than any other researchers in the world.

In 2010, the NFL gave Boston University $1 million, designated the center as the ā€œpreferredā€ brain bank of the NFL and pledged to encourage retired players to donate their brains and participate in the centerā€™s research. The open-ended agreement, signed by Jeff Pash, the NFLā€™s general counsel and No. 2 executive, was framed on the wall of the Boston centerā€™s main office. The agreement came with no strings attached, but some researchers questioned whether Boston University had sacrificed its independence by taking money from the NFL. As Omalu made his case to Tyler Seau, he pointed out that his group didnā€™t take a dime from the league.

Nowinski, Boston Universityā€™s brain chaser, contacted Chao, who was representing Seauā€™s family. ā€œThe pitch is usually, ā€˜Weā€™d like to talk,ā€™ā€ Nowinski said. ā€œWe donā€™t want people to make the ask for us.ā€ Before long, though, ā€œthere were multiple people callingā€ on BUā€™s behalf, Nowinski acknowledged. ā€œPeople who supported us, who had a relationship with them.ā€

The BU group touted itself to the Seaus as the NFLā€™s officially sanctioned brain bank.

The morning after Seauā€™s death, at 5:55 a.m., Sports Illustrated NFL writer Peter King tweeted: ā€œDedicated researchers in Boston studying deceased playersā€™ brains for evidence of trauma attempting to obtain Junior Seauā€™s. Hope they do.ā€

Kingā€™s tweet quickly became a national news story that appeared on NFL.com, ESPN.com and other websites. Seauā€™s family was outraged. ā€œI think that put added pressure on the Seau family,ā€ Nowinski said. ā€œWe heard back from Dr. Chao that they were upset that they were put under that pressure.ā€

Nowinski and others at Boston University urged King to retract the tweet and apologize to the Seaus. Nowinski said the tweet was premature and was based on an earlier conversation in which he told King that BU sought all brains of deceased athletes involved in contact sports. But King, in fact, had confirmed BUā€™s interest in Seauā€™s brain. He refused to apologize or make a retraction. ā€œI empathize with them and know how badly they wanted to see Seauā€™s brain,ā€ King said in an interview. ā€œI was sorry it put them in an awkward situation, because I believe in what they do.ā€

King issued another tweet at 11:13 a.m.: ā€œTo clarify researchers seeking Seauā€™s brain: Info not from them. They seek to examine all ex-players who played contact sports. Every one.ā€

In some ways, the tension was understandable. If Seauā€™s brain was to be studied, it had to be preserved. There were no immediate plans to do that. As he prepared for Seauā€™s autopsy, Nelson tried to keep up with the calls.

Nelson and the Seaus found the competition bizarre and macabre. ā€œIt felt sometimes to me like buzzards were circling,ā€ Nelson said. ā€œI have a scientific mind and a medical background, but when someone has just died, things are very fresh. I want to say, ā€˜Listen, guys, somebodyā€™s dad just died, thatā€™s what my focus is.ā€™ Imagine that your parent dies and then hours later somebody is calling you and saying, ā€˜Hey, would you consider donating this for research?ā€™ It can sit a little odd, and when itā€™s such an unexpected death, it makes it harder.ā€

When she heard about the requests, Seauā€™s ex-wife, Gina, with whom Seau had remained close, was horrified. ā€œIt was the most foreign thing Iā€™d ever heard of, quite honestly,ā€ she said. ā€œAnd the fact that I had to have a conversation with the coroner and ask, ā€˜If we decide to donate it, how do you take it out? And what do you do with it?ā€™ It was the most bizarre, horrible conversation, looking back.ā€

On May 3, the day after Seauā€™s death, Omalu arrived in San Diego around 7:30 a.m. and headed straight to the medical examinerā€™s office. Nelson, believing Omalu had received consent from Seauā€™s family, authorized him to participate in the autopsy. That morning, when the brain donation consent form still hadnā€™t materialized, Nelson asked Davis, the chaplain, to call Tyler Seau and have him forward it. Before the autopsy began, Omalu chatted with Davis, recounting his early battles with the NFL. He then joined Nelson in the autopsy room, a large space with fluorescent lighting and 12 workstations equipped with stainless steel tables, oscillating saws and plastic cutting boards.

Nelson conducted the autopsy and removed most of Seauā€™s vital organs. Omalu said he removed the brain and spinal cord and handled the preservation and cutting of the brain, which, when removed, has the consistency of Jell-O. Part of Seauā€™s brain was placed in formalin (formaldehyde and water), a process known as fixing. The process hardens the brain until it can be sliced more easily and shaved into slivers viewable under a microscope. The rest of Seauā€™s brain was to be frozen and overnighted to Prusiner the next day, according to Omalu.

As the autopsy was concluding, Davis received a call back from Tyler, who was angry and yelling, insisting that he didnā€™t want Omalu near his father. Davis asked why. Tyler responded that he had ā€œtalked to the NFLā€ and specifically mentioned he had received advice from Chao, although it was unclear to Davis whether Tyler might have spoken with others affiliated with the league, too.

When Davis walked in and recounted to Omalu his jconversation with Tyler, Omalu became upset. He felt like it was a replay of the earlier attempts to discredit him, a campaign that was led by three former researchers on the NFLā€™s concussion committee: Elliot Pellman, Ira Casson and Dave Viano. ā€œIt reminded me of the way Casson, Pellman and Viano dismissed me, actually calling me a fraud as well,ā€ Omalu said. ā€œItā€™s the same pattern. To summarize it: a systematic effort to marginalize me, delegitimize me and dismiss me. To pretty much make me null and void, an outsider not to be trusted. Why? I donā€™t know.ā€

ā€œWhy do I deserve to be treated the way Iā€™m being treated?ā€ Omalu said, growing emotional. ā€œFor doing good work? Isnā€™t that what America is about: doing good work, enhancing the lives of others?ā€

Tyler Seau said he was upset that Omalu assisted on the autopsy without his written consent to harvest his fatherā€™s brain. When Tyler read the consent form, he said, he believed it would have forced him to give up all control of his fatherā€™s brain. He declined to address his conversation with Davis but acknowledged in a statement that Chao, the Chargers doctor, had warned him away from Omalu

Even after he was booted from the autopsy room and sent packing, Omalu held out hope that the combination of him, Prusiner and Bailes might still persuade Seauā€™s family to let them study the brain.

Omalu returned home late that night to a congratulatory email from Prusiner. The Nobel laureate attached an article from ESPN.com, which had learned that Omalu participated in the autopsy.

ā€œYour trip to San Diego was really important,ā€ Prusiner wrote. ā€œPlease see the wonderful attached write-up about you, the CTE identifier. I shall call Tyler and David Chao tomorrow and create a time to meet them in SD.ā€

But Prusiner, who declined to be interviewed for this story, appears to have been unaware of the forces now working against them, and that Chao and others were steering the brain in a different direction.

Shortly after Seauā€™s death, Chao called Guskiewicz, an influential member of the NFLā€™s Head, Neck and Spine committee who is also director of the Matthew Gfeller Sport-Related Traumatic Brain Injury Research Center at The University of North Carolina in Chapel Hill. The two men knew each other through a trainer at UNC. In 2011, Guskiewicz, a former critic of the NFL, won a $500,000 MacArthur ā€œgenius grantā€ for his concussion research.

Guskiewicz had been present for Omaluā€™s graphic 2009 presentation of the Webster autopsy and had never forgotten it. He acknowledged to ā€œOutside the Linesā€ and ā€œFrontlineā€ that he shared with Chao concerns ā€œwithin the circles that I hang out in within the science communityā€ that Omalu was prone to ā€œsensationalizing at timesā€ and ā€œshowing slides of the deceased person ā€” their brain ā€” and that sort of thing.ā€

But Guskiewicz and some of his colleagues on the NFL committee also had concerns about Boston University, the leagueā€™s preferred brain bank. Many researchers, including Guskiewicz, complained that BU refused to share brain tissue, making it difficult to validate its work. The issue had grown larger as BU diagnosed more and more CTE cases and asserted publicly that the connection between football and brain damage was indisputable.

Guskiewicz and other researchers associated with the NFL believed that the BU group had created unwarranted hysteria about the risks of playing football, even though the prevalence of CTE is unknown.

ā€œAnd then, to know that there was all this knocking on the door, the calls, I just canā€™t imagine going through it,ā€ Guskiewicz said. ā€œIt puts a bit of a black mark on the entire neuroscience community because some of us, I think, are perhaps guilty by association. So I think thatā€™s concerning.ā€

Around the same time, Ellenbogen, the Head, Neck and Spine committeeā€™s co-chair, said he received a call from the league office in New York. Ellenbogen, in an interview, said he was told that Chao contacted the league seeking advice on behalf of Seauā€™s family. The league wanted the committee to get involved, asking: ā€œIs this something for NIH?ā€

Members of the NFLā€™s concussion committee, including Ellenbogen and Guskiewicz, had pushed the idea of directing research to the NIH since the committee was reconstituted in 2010. In early 2011, despite the leagueā€™s commitment to BU, members tried to direct the brain of former Chicago Bears safety Dave Duerson to the NIH. Unlike Seau, Duerson had left a suicide note in which he requested: ā€œPLEASE, SEE THAT MY BRAIN IS GIVEN TO THE N.F.L.ā€™S BRAIN BANK.ā€

At the time, Duersonā€™s family interpreted the note to mean the Boston University group, which emphasized its association with the NFL. BU diagnosed Duerson with CTE.

With Seau, the NFL did not honor its commitment to BU.

Guskiewicz said he was unaware that the league had pledged to direct brains to Boston University and got involved only because of his personal connection with Chao. He said he viewed the NIH as an ideal solution to end the ā€œtug of warā€ over Seauā€™s brain. He said he believed some of the tissue would ā€œlikely end up in the labs of some of these scientistsā€ and the findings ā€œcould be corroborated using a more collaborative investigative model.ā€

Asked in an interview why they suggested the NIH, Ellenbogen said, ā€œWe had been talking about it for a while. My point, for a long time Iā€™ve been saying ā€¦ if youā€™ve got a problem you want to solve, do you put one university on it or have multiple studies done? The federal government is very good, in some ways, really good about doing this. They donā€™t have an agenda.ā€

Ellenbogen and Guskiewicz put Chao in touch with Dr. Russell Lonser, then an NIH brain researcher. ā€œWe hooked him up with Russ, and then Russ takes the story from there,ā€ Ellenbogen said.

Lonser had two official titles: chief of surgical neurology at the NIH and head of research for the NFLā€™s concussion committee.

Lonser downplayed his connection with the league and said his most important role was overseeing the study of Seauā€™s brain for NIH.

ā€œNIH can be like Switzerland in a certain sense,ā€ he said.

Nowinski said he wasnā€™t surprised by the snub of Boston University: ā€œThe family was upset with us. I didnā€™t think weā€™d get it.ā€

Robert Cantu, the chief of surgery at Emerson Hospital in Concord, Mass., and a co-founder of the Boston University center, described the move as ā€œa personal insultā€ to McKee, the neuropathologist who diagnoses brains for the center. Except for that, said Cantu, a senior adviser to the NFL Head, Neck and Spine committee, he was ā€œglad it went down the way it didā€ because the NIHā€™s confirmation was ultimately stronger than if BU had diagnosed ā€œone more brain.ā€ McKee did not respond to interview requests.

The NIH has not publicly identified the researchers who conducted the blind study of Seauā€™s brain, but Aiello, the NFL spokesman, said he understood Boston University was one of the groups that received Seauā€™s tissue to study. When asked how the NFL would know the identities of the organizations involved in a blind study, he said he ā€œheard it second-hand around the office.ā€

Four months after the Seau family donated Seauā€™s brain to the NIH, the NFL gave $30 million to the institution for concussion and other research. At the time, it was the largest philanthropic gift in the leagueā€™s 92-year history. Goodell said the donation came with no strings attached ā€” a pledge identical to one the NFL made three years earlier to Boston University.

ā€œI donā€™t think you tell the NIH what to expect,ā€ Goodell told ESPNā€™s Darren Rovell. ā€œWe give them the money because they are the leading scientists in the world, and they make the determinations where that money goes, how it can be best spent and what kind of results can be expected.ā€

Ellenbogen said it was important to find a more independent research model.

ā€œYou canā€™t have the NFL doing studies,ā€ Ellenbogen said about the committeeā€™s reasoning. ā€œYou canā€™t have the NFL paying Boston University to be doing studies. You gotta get people who donā€™t owe us anything.ā€


Members of Seauā€™s family were unaware of the full extent of the NFLā€™s role in steering Seauā€™s brain to the NIH. Nor do they appear to care, only that the competition for the brain stopped and the study was of the highest quality. ā€œI didnā€™t care about what people and doctors were competing for,ā€ said Gina Seau, Seauā€™s ex-wife. ā€œI just cared about a high level of scientific study without bias.ā€

The confirmation of CTE is, of course, no solace to Seauā€™s relatives and friends. But it provides an explanation for why he became a different person.

Rather than providing the closure, Tyler Seau said the diagnosis in some ways made him feel worse. ā€œIt didnā€™t take any of the pain away; I feel it almost brought more,ā€ he said. ā€œMainly because I feel bad that I didnā€™t try harder. And just the pain that he was going through for how many years?ā€

Fitzsimmons, the lawyer who represented Webster, said itā€™s too soon to know what to expect next from the NFL.

Fitzsimmons has been following the leagueā€™s struggle to deal with concussions for nearly 20 years. He defeated the NFL in court to win $1.8 million in disability benefits for Webster ā€” three years after Websterā€™s death. He watched the NFL try to discredit and marginalize Omalu. He watched the league embrace Boston University and now push its researchers aside for the NIH.

ā€œIf you can control facts,ā€ Fitzsimmons said, ā€œthatā€™s probably beneficial to whatever side is controlling them.ā€

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